Description
This medication is available by prescription only and requires a veterinarian/patient relationship and current heartworm test
In clinical field trials with HEARTGARD Plus (ivermectin/pyrantel), vomiting or diarrhea within 24 hours of dosing was rarely observed (1.1% of administered doses). The following adverse reactions have been reported following the use of HEARTGARD Plus: Depression/lethargy, vomiting, anorexia, diarrhea, mydriasis, ataxia, staggering, convulsions and hypersalivation.
HEARTGARD Plus (ivermectin/pyrantel) Chewables are well tolerated. All dogs should be tested for heartworm infection before starting a preventive program. Following the use of HEARTGARD Plus, digestive and neurological side effects have rarely been reported. For more information, contact your veterinarian or refer to the full prescribing information.
Ivermectin and Pyrantel

